People who flavor
their diets with plenty of onions
and garlic might have lower odds
of several types of cancer, a new
study suggests.
In an analysis of eight studies from
Italy and Switzerland, researchers
found that older adults with the highest
onion and garlic intakes had the lowest
risks of a number of cancers -- including
colon, ovarian and throat cancers.
The findings, which appear in the
American Journal of Clinical Nutrition,
are in line with some past research.
But those studies were mainly conducted
in China, and it is unclear if the
results are different in Western countries.
Dietary habits are substantially
different in China, with garlic intake,
in particular, being far higher, Dr.
Carlotta Galeone, the lead author
of the new study stated.
These latest findings suggest the
anti-cancer benefit of these vegetables
extend to Western populations, according
to Galeone, a researcher at the Mario
Negri Institute of Pharmacologic Research
in Milan, Italy.
It's still not certain that onions
and garlic have a direct effect on
cancer risk. It's possible, for instance,
that onion and garlic lovers also
have an overall diet that protects
against cancer, according to Galeone
and her colleagues.
On the other hand, they note, animal
studies and lab experiments with cancer
cells have found that certain compounds
in onions and garlic may inhibit the
growth of tumors. Sulfur compounds
found in garlic and antioxidant flavonoids
in onions are among the potentially
protective substances.
The current findings are based on
results from eight studies conducted
in Italy and Switzerland. Each study
compared healthy older adults to patients
with a particular form of cancer,
asking participants for detailed information
on their diets, physical activity
and other lifestyle habits.
When it came to colon cancer, Galeone's
team found that men and women who
ate seven or more servings of onions
per week had less than half the risk
of those who shunned the vegetable.
Similarly, garlic lovers were a quarter
less likely to develop the disease
than people who maintained garlic-free
diets.
The vegetables were also linked to
lower risks of cancers of the mouth,
throat, kidneys and ovaries.
Given what's known about the biological
activity of some onion and garlic
compounds, it wouldn't be a bad idea
to spice up your diet with the vegetables,
according to Galeone.
It's probably wise to mix them with
plenty of other vegetables, however.
Some research has found that garlic
and tomatoes may have "synergistic"
cancer-fighting effects, Galeone and
her colleagues note. And, in general,
experts recommend that people eat
a variety of fruits and vegetables
every day for overall health.
SOURCE: American Journal of Clinical
Nutrition, November 2006.