A fiber-rich diet may help control levels of a
blood protein linked to an increased risk of heart
disease, new research suggests.
In a study of 524 healthy adults, investigators
found that those with the highest fiber intake had
lower blood levels of C-reactive protein (CRP) than
those who ate the least fiber. CRP is a marker of
ongoing inflammation in the body, and consistently
high levels of this protein have been identified
in previous studies as a risk factor for future
heart disease.
The new findings support the general recommendation
that adults get 20 to 35 grams of fiber per day,
in the form of fruits, vegetables, beans and whole
grains.
Unfortunately, they note in their report in the
American Journal of Clinical Nutrition, the average
American consumes only half that amount, lead investigator
Dr. Yunsheng Ma of the University of Massachusetts
Medical School in Worcester and colleagues point
out.
For their study, the researchers measured the participants'
CRP levels five times over the course of a year
and collected information on diet, exercise habits
and other health factors.
About 18 percent of men and women had elevated
CRP levels, above 3 milligrams per liter of blood.
But CRP levels generally dipped as fiber intake
increased. Compared with subjects who ate the least
fiber, those who ate the most were 63 percent less
likely to have an elevated CRP number.
It did not take a ton of roughage to reap the benefit,
the researchers found. Study participants with the
highest fiber intake typically got about 22 grams
per day, or just within the recommended range.
Ongoing, low-level inflammation in the body is
thought to contribute to a range of ills, including
clogged arteries and heart disease.
It's not clear why fiber may reduce inflammation,
according to Ma's team, but it may lower cholesterol
and blood sugar, both of which can contribute to
inflammation.
"This study," the researchers write, "suggests
that a diet high in fiber may play a role in reducing
inflammation and, thus, the risk of cardiovascular
disease and diabetes."
In addition, both of the main forms of fiber, soluble
and insoluble, were related to lower CRP levels.
Soluble fiber is found in foods like oatmeal, beans,
berries and apples, while whole grains and many
vegetables are good sources of insoluble fiber.
All of these foods, the study authors write, should
become the "foundation of America's diet to combat
heart disease and diabetes."
SOURCE: American Journal of Clinical Nutrition,
April 2006.